Name

Tomographie en Cohérence Optique de la choroïde par le module Enhanced Depth Imaging dans la choriorétinopathie séreuse centrale

Choroidal abnormalities are associated with the pathogenesis of various disorders affecting the retina including central serous chorioretinopathy (CSC). In recent years, detecting the choroid using spectral-domain optical coherence tomography (SD-OCT) has often been difficult, because the retinal pigment epithelium hinders the penetration process. Enhanced depth imaging (EDI) OCT is a recent modification of the standard technique. We aimed to evaluate the choroidal thickness (CT) using Enhanced Depth Imaging Spectral Domain Optical Coherence Tomography (EDI-SD-OCT) in patients with central serous chorioretinopathy (CSC).

We included prospectively patients with acute or chronic CSC, from April 2019 to November 2019. Subfoveal choroidal thickness (SFCT) was measured as the distance between the outer border of the retinal pigment epithelium-Bruch’s membrane complex, and the chorioscleral border under the fovea. SFCT was measured using EDI-OCT. Each measurement for a patient presenting a CSC was followed by the same measurement in a healthy subject.

Thirty six eyes of 28 patients diagnosed with acute or chronic CSC, were included. The mean patient age was 38.3 ± 11 years (range, 22–59 years). Among the 36 eyes, 21 had acute CSC and 15 had chronic CSC. SFCT measured with EDI-OCT was 318.6 ± 82.6 μm in acute and 374.1 ± 102.7 μm in chronic CSC. The SFCT was significantly greater in CSC eyes than in fellow eyes (p<0.001). The chronic form was associated to greater SFCT than the acute presentation (p<0,001).

EDI is a recently standardized technique for imaging the choroid more clearly using commercial SD-OCT. The EDI-OCT occasionally requires the contrast to be set in order to trace the chorioscleral borders clearly. Normal subfoveal choroidal thickness varies widely among reports. Most studies reported the subfoveal choroidal thickness measured with EDI-OCT in CSC to be greater than that in normal eyes.

EDI-SD-OCT demonstrated a very thick choroid in patients with CSC. This finding provides additional evidence that CSC may be caused by the hyperdynamic circulation increasing hydrostatic pressure in the choroid.